2010 Mercedes-Benz E350 Problems, Recalls & Reliability
Verdict
CautionComplaint Index
69/100
#5 most-complained of 14 E350 years
The 2010 Mercedes-Benz E350 has a Complaint Index of 69 and ranks 5th worst of 14 model years, earning a Caution verdict. Airbags are the top problem area with 68 complaints (38% share) and 4 recalls total.
- Complaints
- 180
- Recalls
- 4
- Crashes / fires
- 9 / 0
- Injuries / deaths
- 6 / 0
- NHTSA overall rating
- Not rated
- EPA combined MPG
- 20
- 17 city / 26 hwy
Top 2010 Mercedes-Benz E350 problems
NHTSA owner complaints by component group. Groups with 15+ complaints have their own page.
- Airbags68 (38%)
- Suspension, Wheels & Tires22 (12%)
- Electrical System21 (12%)
- Fuel System20 (11%)
- Other20 (11%)
- Engine18 (10%)
- Brakes17 (9%)
- Structure & Body15 (8%)
- Transmission & Powertrain14 (8%)
- Steering7 (4%)
What owners report
- Airbags failed to deploy in crashes, including a head-on collision and a snow plow impact, sometimes resulting in injuries requiring medical attention.
- Brakes have been reported as unresponsive at low speed, with one owner going through a red light before stopping.
- The transmission has been reported to default into second gear after each start cycle, cutting torque when pulling into traffic.
- Tires reportedly went flat repeatedly on the same vehicle within a short time, with the dealer unable to identify a cause.
- The horn was reported as non-functional when the vehicle was turned off, even while parked.
- Owners reported wind pressure entering through open windows at highway speed, described as affecting balance and nearly causing a crash.
2010 Mercedes-Benz E350 recalls
4 NHTSA recall campaigns list this model year.
- NHTSA 22V168000Mar 18, 2022Engine22 vehicles
Engine and engine cooling:engine:engine control module (ecu/ECM):software
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been updated with incorrect software configuration during a service repair. This can result in various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions, including stability and traction control.
Risk: Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control, can increase the risk of a crash.
Remedy: Dealers will update the software configuration on the affected control units, free of charge. Owner notification letters were mailed May 3, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040003.
- NHTSA 18V043000Jan 10, 2018Airbags132,167 vehicles
Air bags:frontal:passenger side:inflator module
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2013 C250, C250 Coupe, C350 Coupe 4Matic, C300 4Matic, C350, C350 Coupe, C63 AMG, C63 Coupe, E350 Cabrio, E350 Coupe, E550 Cabrio, E350 Coupe 4Matic, E550 Coupe, GLK350 4Matic, GLK250 Bluetec 4Matic, GLK350, SLS Coupe, SLS AMG GT Coupe, and SLS Roadster vehicles sold, or ever registered, in the states of Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands or "Zone A." Additionally, MBUSA is recalling certain 2010 C300, C300 4Matic, C63 AMG, E350 Coupe, E550 Coupe, GLK350, and GLK350 4Matic vehicles ever registered in the states of Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia or "Zone B." MBUSA is also recalling certain 2009 C300, C300 4Matic, C63 AMG, and C350 vehicles ever registered in the states of AK, CO, CT, ID, IA, ME, MA, MI, MN, MO, NH, NY, ND, OR, RI, SD, UT, VT, WA, WI and WY or "Zone C." In the event of a crash necessitating deployment of the passenger frontal air bag, these passenger air bag inflator may explode due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.
Risk: An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.
Remedy: MBUSA will notify owners, and dealers will replace the passenger frontal air bag module, free of charge. Mercedes issued an interim notification to owners on February 23, 2018. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.
- NHTSA 16V363000May 26, 2016Airbags258,163 vehicles
Air bags:frontal:passenger side:inflator module
Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 2011 SLS AMG, E350 Convertible, E550 Coupe and E550 Convertible vehicles originally sold, or ever registered, in Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands, or "Zone A." Additionally, unless included in "Zone A" above, MBUSA is recalling certain model year 2008 C300 Sedan, C350 Sedan, C63 AMG Sedan and C300 4-Matic Sedan vehicles originally sold, or ever registered, in Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia, or "Zone B." Vehicles not originally sold or ever registered in either Zones A or B are not subject to this safety recall. These vehicles are equipped with certain air bag inflators assembled as part of the passenger frontal air bag modules, and used as original equipment or replacement equipment. In the event of a crash necessitating deployment of the front air bags, these inflators may rupture due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.
Risk: An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.
Remedy: MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of charge. Owners were sent an interim notification October 2016. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.
2010 Mercedes-Benz E350 fuel economy and fuel cost
- City
- 17 MPG
- Highway
- 26 MPG
- Combined
- 20 MPG
- Annual fuel cost (EPA)
- $4,000
- 15,000 mi/yr
- Fuel
- Premium
- Current regular gas
- $4.32/gal
- national avg.
EPA figures; median across configurations of this model year. Estimate your own cost with the fuel cost calculator.
2010 compared with other E350 years
Frequently asked questions
- Is the 2010 Mercedes-Benz E350 reliable?
- NHTSA data gives the 2010 E350 a Complaint Index of 69 and a Caution verdict, ranking it 5th worst among 14 model years of the E350.
- What is the biggest problem with the 2010 Mercedes-Benz E350?
- Airbags are the top problem area, accounting for 68 of 180 total complaints (38% share), with a median failure mileage of 54,978 miles.
- Does the 2010 Mercedes-Benz E350 have any recalls?
- NHTSA lists 4 recalls for the 2010 E350, covering the engine control units and airbag modules; none are do-not-drive recalls.
- How does the 2010 E350 compare to other years?
- With a Complaint Index of 69, the 2010 E350 is better than 2011-2014 (all rated Avoid, indexes 77-100) but worse than 2015-2017 and 2020-2024, which rank Good or Best.
- What is the fuel economy of the 2010 Mercedes-Benz E350?
- EPA rates the 2010 E350 at 20 mpg combined (17 city / 26 highway), with an estimated annual fuel cost of $4,000.