2025 Mercedes-Benz E350 Reliability Data: Problems & Recalls
No verdict The 2025 Mercedes-Benz E350 has a complaint index of 44, ranking 11th out of 19 model years, with 2 complaints and 2 recalls, including a do-not-drive recall for a rear axle bracket weld defect.
Based on NHTSA complaints per model-year, not a reliability rating. Methodology
YearToAvoid Scorecard
- Complaint Index
- 44/100
- #11 of 19 E350 years
- Verdict
- No verdict
- vs. other years of this model
- Complaints
- 2
- unique NHTSA reports
- Recalls
- 2
- 1 Do Not Drive
- Crashes
- 0
- reported in complaints
- Fires
- 0
- Injuries
- 0
- Top issue
- Electrical System
- NHTSA overall rating
- Not rated
- EPA combined MPG
- 27.5
- 24.5 city / 33 hwy
- Injuries / deaths
- 0 / 0
Top 2025 Mercedes-Benz E350 problems
Share of this year’s NHTSA complaints by component group. Groups with 15+ complaints have their own page.
- Electrical System1 (50%)
- Engine1 (50%)
- Other1 (50%)
- Visibility & Wipers1 (50%)
A complaint can list more than one component, so shares add up to more than 100%. Shares are % of complaints.
What owners report
- Engine can hydrolock after driving through standing water, with the alternator and starter failing as a result.
- Some owners needed a full engine replacement after water intrusion damage.
- The digital instrument cluster and center infotainment display have gone completely black while the vehicle was in motion.
- Loss of the instrument display removes speed, gear position, and safety warning indicators from the driver's view while driving.
2025 Mercedes-Benz E350 recalls
2 NHTSA recall campaigns list this model year.
- NHTSA 26V281000May 1, 2026Electrical System144,049 vehicles
Electrical system: instrument cluster/panel
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024-2026 AMG GT, C-Class, E-Class, SL, CLE, and GLC vehicles. The infotainment control unit may reset while the vehicle is in motion and cause the instrument panel display to go blank.
Risk: An instrument panel display that fails to show critical safety information, such as the speedometer and warning lights, increases the risk of a crash.
Remedy: Dealers will update the infotainment control unit software, free of charge. Owner notification letters were mailed June 29, 2026. MBUSA's number for this recall is 2026050004. Owners may contact MBUSA customer service at 1-800-367-6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning May 8, 2026.
- NHTSA 24V941000Dec 18, 2024Transmission & Powertrain17 vehiclesDo Not Drive
Power train:axle assembly
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2025 E 350, E 350 4MATIC, E 450 4MATIC, and E450 4MATIC station wagon vehicles. The camber strut bracket may have been improperly welded onto the rear axle carrier, possibly resulting in separation of the bracket from the rear axle carrier.
Risk: Rear axle carrier failure can cause a sudden loss of vehicle handling and control, increasing the risk of a crash.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will replace the rear axle carrier, free of charge. Owner notification letters were mailed January 22, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024120015.
2025 Mercedes-Benz E350 fuel economy and fuel cost
- City
- 24.5 MPG
- Highway
- 33 MPG
- Combined
- 27.5 MPG
- Annual fuel cost (EPA)
- $2,900
- 15,000 mi/yr
- Fuel
- Premium
- Current regular gas
- $4.32/gal
- national avg.
EPA figures; median across configurations of this model year. Estimate your own cost with the fuel cost calculator.
2025 compared with other E350 years
Frequently asked questions
- Is the 2025 Mercedes-Benz E350 reliable?
- NHTSA lists only 2 complaints for the 2025 E350, giving it a complaint index of 44, which ranks 11th out of 19 E350 model years. It has 2 recalls, one of which is a do-not-drive recall.
- Does the 2025 Mercedes-Benz E350 have a recall?
- Yes. It has a do-not-drive recall (24V941000) for a rear axle carrier camber strut bracket that may have been improperly welded, and a second recall (26V281000) for an infotainment control unit that may reset while driving.
- What is the top reported problem on the 2025 E350?
- NHTSA data shows the Electrical System as the top problem area, tied with the Engine and Visibility & Wipers, each accounting for 50% of the sample complaint share.
- How does the 2025 E350 compare to other E350 years?
- The 2025 E350 has a complaint index of 44 and ranks 11th worst out of 19 years tracked. Years like 2006 and 2007 have much higher complaint indexes of 100 and 89 and are rated Avoid, while 2024 has an index of just 6 and is rated Best.
- What is the fuel economy of the 2025 Mercedes-Benz E350?
- The 2025 E350 gets an EPA-rated 27.5 mpg combined (24.5 city / 33 highway), with an estimated annual fuel cost of $2,900.