2025 Mercedes-Benz E350 Problems, Recalls & Reliability
Verdict
No verdictComplaint Index
54/100
#7 most-complained of 14 E350 years
The 2025 Mercedes-Benz E350 has a complaint index of 54, ranking 7th worst out of 14 model years for the E350. NHTSA lists 2 complaints and 2 recalls, including 1 do-not-drive recall for a rear axle welding defect.
- Complaints
- 2
- Recalls
- 2
- incl. Do Not Drive
- Crashes / fires
- 0 / 0
- Injuries / deaths
- 0 / 0
- NHTSA overall rating
- Not rated
- EPA combined MPG
- 27.5
- 24.5 city / 33 hwy
Top 2025 Mercedes-Benz E350 problems
NHTSA owner complaints by component group. Groups with 15+ complaints have their own page.
- Electrical System1 (50%)
- Engine1 (50%)
- Other1 (50%)
- Visibility & Wipers1 (50%)
2025 Mercedes-Benz E350 recalls
2 NHTSA recall campaigns list this model year.
- NHTSA 26V281000May 1, 2026Electrical System144,049 vehicles
Electrical system: instrument cluster/panel
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024-2026 AMG GT, C-Class, E-Class, SL, CLE, and GLC vehicles. The infotainment control unit may reset while the vehicle is in motion and cause the instrument panel display to go blank.
Risk: An instrument panel display that fails to show critical safety information, such as the speedometer and warning lights, increases the risk of a crash.
Remedy: Dealers will update the infotainment control unit software, free of charge. Owner notification letters were mailed June 29, 2026. MBUSA's number for this recall is 2026050004. Owners may contact MBUSA customer service at 1-800-367-6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning May 8, 2026.
- NHTSA 24V941000Dec 18, 2024Transmission & Powertrain17 vehiclesDo Not Drive
Power train:axle assembly
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2025 E 350, E 350 4MATIC, E 450 4MATIC, and E450 4MATIC station wagon vehicles. The camber strut bracket may have been improperly welded onto the rear axle carrier, possibly resulting in separation of the bracket from the rear axle carrier.
Risk: Rear axle carrier failure can cause a sudden loss of vehicle handling and control, increasing the risk of a crash.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will replace the rear axle carrier, free of charge. Owner notification letters were mailed January 22, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024120015.
2025 Mercedes-Benz E350 fuel economy and fuel cost
- City
- 24.5 MPG
- Highway
- 33 MPG
- Combined
- 27.5 MPG
- Annual fuel cost (EPA)
- $2,900
- 15,000 mi/yr
- Fuel
- Premium
- Current regular gas
- $4.32/gal
- national avg.
EPA figures; median across configurations of this model year. Estimate your own cost with the fuel cost calculator.
2025 compared with other E350 years
Frequently asked questions
- Is the 2025 Mercedes-Benz E350 reliable?
- NHTSA shows a complaint index of 54 for the 2025 E350, placing it 7th worst among the 14 model years with data. It has fewer complaints than many earlier E350 years but carries a serious recall.
- Does the 2025 Mercedes-Benz E350 have a recall?
- Yes. NHTSA lists 2 recalls for the 2025 E350. One is a do-not-drive recall (24V941000) covering a rear axle camber strut bracket that may have been improperly welded, and the other addresses an infotainment control unit that may reset while driving.
- What is the top problem area for the 2025 E350?
- NHTSA data lists Electrical System as the top problem area, with 1 of the 2 recorded complaints tied to it, alongside 1 complaint each for Engine and Visibility & Wipers issues.
- How does the 2025 E350 compare to other E350 years?
- The 2025 E350's complaint index of 54 ranks 7th worst of 14 model years. Years like 2017, 2021, 2022, and 2024 score lower and carry a Best verdict, while 2011-2014 carry Avoid verdicts with much higher complaint indexes.
- What is the fuel economy of the 2025 Mercedes-Benz E350?
- EPA rates the 2025 E350 at 27.5 mpg combined (24.5 city / 33 highway), with an estimated annual fuel cost of $2,900.