YearToAvoid

2021 Mercedes-Benz S 580 Problems, Recalls & Reliability

Verdict

No verdict

Complaint Index

100/100

#1 most-complained of 3 S 580 years

Based on NHTSA complaints per model-year, not a reliability rating. Methodology

Among the 3 model years with data, 2021 ranks worst with a Complaint Index of 100 and 33 complaints, led by Electrical System issues (33%). NHTSA lists 16 recalls for this year, more than 2022 (7) or 2023 (5).

Complaints
33
Recalls
16
Crashes / fires
2 / 0
Injuries / deaths
3 / 1
NHTSA overall rating
Not rated
EPA combined MPG
19.5
16.5 city / 24.5 hwy

Top 2021 Mercedes-Benz S 580 problems

NHTSA owner complaints by component group. Groups with 15+ complaints have their own page.

  1. Electrical System11 (33%)
  2. Engine9 (27%)
  3. Suspension, Wheels & Tires9 (27%)
  4. Other6 (18%)
  5. Collision Avoidance & Cameras5 (15%)
  6. Brakes3 (9%)
  7. Lane Departure3 (9%)
  8. Fuel System2 (6%)
  9. Transmission & Powertrain2 (6%)
  10. Visibility & Wipers2 (6%)

What owners report

  • Rearview camera fails to display when shifting into reverse, sometimes clearing itself after the car is restarted
  • Cruise control unexpectedly reduces speed on the highway after the driver presses a steering-wheel button
  • Brake pedal fails to slow the car at low speed, in one case resulting in a crash
  • Dashboard reflects onto the windshield and obstructs the driver's forward view
  • 12-volt battery displays repeated 'critical charge' warnings and the car drops speed on the highway without warning
  • Low-profile tires suffer blowouts after hitting potholes, with owners citing the factory Pirelli tires as the weak point
2021 Mercedes-Benz S 580 complaints: complaints filed per month7Jul 2021Jan 2022Jun 2023Jun 2024Feb 2025Dec 2025Aug 2026
52 complaints filed with NHTSA from Jul 2021 to Aug 2026; peak Jan 2022 (7).

2021 Mercedes-Benz S 580 recalls

16 NHTSA recall campaigns list this model year.

  1. NHTSA 25V116000Feb 24, 2025Brakes20,339 vehicles

    Service brakes, hydraulic:foundation components

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.

    Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.

    Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.

  2. NHTSA 24V807000Oct 25, 2024Other21 vehicles

    Communication: auto crash notification

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S 580 4MATIC, S 500 4MATIC, and S 580 4MATIC vehicles. The emergency call system may fail to place an automatic or manual call and may not provide the vehicle location as intended.

    Risk: A disabled emergency call system that prevents a vehicle occupant from contacting emergency services or fails to identify the vehicle location, can delay emergency responders and increase the risk of injury.

    Remedy: Dealers will update the communication module software, free of charge. Owner notification letters were mailed December 6, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024110002.

  3. NHTSA 24V704000Sep 20, 2024Engine27,190 vehicles

    Engine and engine cooling:engine:engine control module (ecu/ECM):software

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 S580, and Maybach S580 vehicles. In the event of a mechanical failure in the engine Camtronic system, the engine control unit (ECU) software may cause the engine to overheat or stall.

    Risk: An engine stall can increase the risk of a crash. In addition, an engine that overheats can increase the risk of a fire.

    Remedy: Dealers will update the ECU software, free of charge. Owner notification letters were mailed on November 15, 2024. Owner notification letters will be mailed in phases, on November 15, 2024, January 10, 2025, and February 21, 2025. Owners can contact Mercedes-Benz Customer Service at 1-877-496-3691. MBUSA's number for this recall is 2024100007.

See all 16 recalls for the 2021 Mercedes-Benz S 580 →

2021 Mercedes-Benz S 580 fuel economy and fuel cost

City
16.5 MPG
Highway
24.5 MPG
Combined
19.5 MPG
Annual fuel cost (EPA)
$4,100
15,000 mi/yr
Fuel
Premium
Current regular gas
$4.32/gal
national avg.

EPA figures; median across configurations of this model year. Estimate your own cost with the fuel cost calculator.

2021 compared with other S 580 years

Complaint Index by model year (0 = fewest issues, 100 = most)0255075100202120222023
Complaint Index: 0 = fewest issues, 100 = most, relative to other years of this model. Avoid Caution Good Best
YearVerdictIndexComplaintsRecallsMPG
2021No verdict100331619.5
2022No verdict50257 !18.5
2023No verdict06518.5

All Mercedes-Benz S 580 years: best and worst →

Frequently asked questions

Is the 2021 Mercedes-Benz S 580 the worst year for this model?
Among the 3 model years with data, 2021 has the highest Complaint Index (100) and the most complaints (33), ranking worst of the three.
What is the top problem area for the 2021 S 580?
Electrical System complaints lead, making up 33% of all complaints, followed by Engine and Suspension, Wheels & Tires at 27% each.
How many recalls does the 2021 Mercedes-Benz S 580 have?
NHTSA lists 16 recalls for the 2021 S 580, covering brakes, engine, fuel system, electrical system, and other components.
At what mileage do 2021 S 580 problems typically show up?
Median mileage at failure is 1,000 miles for Electrical System complaints, 976 miles for Engine complaints, and 3,000 miles for Suspension, Wheels & Tires complaints.
Were there any crashes or injuries reported for the 2021 S 580?
NHTSA data shows 2 crashes, 3 injuries, and 1 death reported among the 2021 S 580 complaints.

Sources: NHTSA Office of Defects Investigation complaint and recall databases; U.S. EPA fuel economy data; NHTSA 5-Star Safety Ratings. Complaints are unverified owner reports.

Data updated Sep 24, 2026. Read the methodology and data sources. The Complaint Index is based on NHTSA owner complaints and recalls; it is not a reliability rating.