YearToAvoid

2021 Mercedes-Benz Gls450 Problems, Recalls & Reliability

Verdict

Avoid

Complaint Index

80/100

#2 most-complained of 6 Gls450 years

Based on NHTSA complaints per model-year, not a reliability rating. Methodology

The 2021 Mercedes-Benz Gls450 ranks 2nd worst out of 6 model years, with a Complaint Index of 80 and 30 complaints tied to 12 recalls. Electrical System issues, mostly 48-volt battery failures, dominate at 47% of complaints, some causing stalls and two fires.

Complaints
30
Recalls
12
Crashes / fires
1 / 2
Injuries / deaths
1 / 0
NHTSA overall rating
Not rated
EPA combined MPG
21
20 city / 24 hwy

Top 2021 Mercedes-Benz Gls450 problems

NHTSA owner complaints by component group. Groups with 15+ complaints have their own page.

  1. Electrical System14 (47%)
  2. Other8 (27%)
  3. Engine4 (13%)
  4. Lane Departure3 (10%)
  5. Structure & Body3 (10%)
  6. Collision Avoidance & Cameras2 (7%)
  7. Suspension, Wheels & Tires2 (7%)
  8. Fuel System1 (3%)
  9. Seat Belts1 (3%)
  10. Transmission & Powertrain1 (3%)

What owners report

  • Owners report the 48-volt battery system failing and shutting the vehicle off while driving, including at highway speed in traffic.
  • The dashboard shows warnings such as "48-volt battery failure" and "check engine" before the vehicle loses power and later restarts on its own.
  • Some vehicles would not start on multiple separate occasions and required towing to a dealer for 48-volt battery replacement.
  • Adaptive cruise control has been reported to unexpectedly decelerate the vehicle from highway speed down to as low as 15 mph with no warning light.
  • The Lane Departure system has independently jerked the steering while attempting to avoid a pedestrian or object, and separately caused repeated stalling that nearly led to a crash.
  • One owner reported smoke and fire coming from under the passenger seat, resulting in a total loss of the vehicle.
2021 Mercedes-Benz Gls450 complaints: complaints filed per month9Jul 2021Apr 2022Aug 2022Nov 2022Oct 2023Jul 2024Nov 2024Nov 2025
40 complaints filed with NHTSA from Jul 2021 to Nov 2025; peak Jan 2023 (9).

2021 Mercedes-Benz Gls450 recalls

12 NHTSA recall campaigns list this model year.

  1. NHTSA 24V207000Mar 15, 2024Electrical System116,020 vehicles

    Electrical system:wiring

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 GLE 350, 2020-2024 GLE 450, 2020-2023 GLS 580, GLE 580, 2019-2023 GLS 450, 2021-2023 Maybach GLS 600, AMG GLS 63, 2021-2024 AMG GLE 53, AMG GLE 53 Coupe, and AMG GLE 63 S vehicles. A 48-Volt ground connection under the passenger seat may not be secured properly, resulting in the ground connection overheating.

    Risk: An overheated ground connection can increase the risk of a fire.

    Remedy: Dealers will inspect and tighten the 48-Volt ground connection as necessary, free of charge. Owner notification letters were mailed on May 3, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040002.

  2. NHTSA 24V118000Feb 16, 2024Transmission & Powertrain105,071 vehicles

    Power train:automatic transmission:control module:software

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2023 GLE 450 and GLS 450 vehicles. The transmission may not fully downshift in certain conditions, causing the engine to stall.

    Risk: An engine stall increases the risk of a crash.

    Remedy: Dealers will update the transmission control unit software, free of charge. Owner notification letters were mailed March 29, 2024. Owners may contact MBUSA customer service at 1-800-367-6372.

  3. NHTSA 23V445000Jun 26, 2023Fuel System143,551 vehicles

    Fuel system, gasoline:delivery:fuel pump

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

See all 12 recalls for the 2021 Mercedes-Benz Gls450 →

2021 Mercedes-Benz Gls450 fuel economy and fuel cost

City
20 MPG
Highway
24 MPG
Combined
21 MPG
Annual fuel cost (EPA)
$3,800
15,000 mi/yr
Fuel
Premium
Current regular gas
$4.32/gal
national avg.

EPA figures; median across configurations of this model year. Estimate your own cost with the fuel cost calculator.

2021 compared with other Gls450 years

Complaint Index by model year (0 = fewest issues, 100 = most)0255075100201620172018201920202021
Complaint Index: 0 = fewest issues, 100 = most, relative to other years of this model. Avoid Caution Good Best
YearVerdictIndexComplaintsRecallsMPG
2019Good4024318
2020Avoid100362221
2021Avoid80301221

All Mercedes-Benz Gls450 years: best and worst →

Frequently asked questions

Is the 2021 Mercedes-Benz Gls450 reliable?
Based on NHTSA owner complaints and recalls, the 2021 model ranks 2nd worst of 6 model years with a Complaint Index of 80 and 12 recalls, giving it an Avoid verdict relative to other Gls450 years.
What is the biggest problem with the 2021 Gls450?
The Electrical System is the top problem area, accounting for 47% of complaints (14 of 30), largely tied to 48-volt battery failures reported at a median mileage of 11,000 miles.
Does the 2021 Gls450 have recalls?
Yes, NHTSA lists 12 recalls for the 2021 Gls450, covering the Electrical System, Transmission & Powertrain, Fuel System, HVAC, and Structure & Body, none of which are do-not-drive recalls.
How does the 2021 Gls450 compare to other years?
The 2021 model (Complaint Index 80) is worse than 2018 (20, Best), 2019 (40, Good), and 2017 (60, Caution), but slightly better than 2020 (100, Avoid).
Were there any fires reported in the 2021 Gls450?
NHTSA data shows 2 fire incidents for the 2021 model year, both linked to the Electrical System, with one injury reported and no deaths.

Sources: NHTSA Office of Defects Investigation complaint and recall databases; U.S. EPA fuel economy data; NHTSA 5-Star Safety Ratings. Complaints are unverified owner reports.

Data updated Sep 24, 2026. Read the methodology and data sources. The Complaint Index is based on NHTSA owner complaints and recalls; it is not a reliability rating.